Penyelidik USM Temui Ekstrak Tumbuhan Tempatan Untuk Atasi Obesiti

Penyelidik USM Temui Ekstrak Tumbuhan Tempatan Untuk Atasi Obesiti

Sidang media khas akan diadakan esok, 23 Oktober 2008, jam 11.00 pagi di Bilik Persidangan Canselori, USM bagi membentangkan penemuan terbaru Prof. Zhari Ismail dari Pusat Pengajian Sains Farmasi USM yang mendapatkan ekstrak dari pokok kaduk (pipersarmentosum) serta tumbuhan herba lain yang dapat membantu mengatasi masalah obesiti.Penemuan beliau yang diproses menjadi pil dikatakan telah menunjukkan hasil yang positif dan telah pun dilakukan ujian pra-kilinikal.Obesiti kini menjadi masalah sejagat. Gejala ini menjadi ancaman kesihatan utama kepada masyarakat. Di samping mengamalkan gaya hidup sihat penemuan oleh penyelidik USM ini mampu untuk membantu mereka yang berhasrat mengurangkan berat badan dengan menggunakan NOBESITI. "NOBESITI: Piperamide based antiobesity nutraceutical from local sources.Prof. Dr. Zhari bin IsmailSchool of Pharmaceutical Sciences, Univesiti Sains Malaysia, Minden, PenangCollaborators : Khalid Hussain, Hayder Bahasaab, Amirin Sadikum, Pazilah Ibrahim and Amin Malik.Obesity is due to the excessive deposition of fat and this condition is currently on the rise worldwide. Current common mode of treatment available includes appetite suppressants and laxatives and side effects and complications are often associated with it.Nobesiti is an antiobesity nutraceutical product prepared from local sources and possess novel mechanism of treatment. It inhibits vascularisation of blood vessels to fast growing adepocytes which are involved in adepogenesis.Nobesiti has been evaluated for safety as per OECD guidelines and found to be safe at 2000ng/kg body weight using animal models.Nobesiti has been tested for hepatotoxicity and a range of cell lines and found to be non cytotoxic.Nobesiti has been evaluated for pharmacokinetic parameters (absorption, delivery, metabolism and excretion).Nobesiti has been well characterised and standardised using modern analytical techniques.Nobesiti is easily scaled up for manufacture and has a tremendous market potential worldwide."